The U-Strip – New Rx Compounds | PDF
New Drug Applications for Delivery with the U-Strip Require Three Screening Assessments:
- Ultrasound vs. Drug
- Patch Liberation Test
- Cadaver Skin Delivery Trial
Over 175 Drugs, which are too large for Passive Transdermal Patches, have already been modeled for delivery via the U-Strip, covering a wide range of molecular weights. The largest size molecule tested for transdermal delivery was tPA, at 75, 000 Daltons.
U-Strip Range of Molecular Size
U-Strip is Theorized to be Capable of Delivering From 0 to 125,000 Mol Wt. Compounds
Effects of U-Strip Ultrasound Upon Humulin Reg. Insulin Over Time Vs. Control
Drug candidates can be screened for potential U-Strip Delivery in as little as 3 months. The screening also provides design data for both the Patch and the Sonic Applicator control device.
- Rutgers University: NJ Center for Biomaterials: Laboratory for Drug Delivery
- Philadelphia College of Pharmacy (PCP), University of the Sciences in Philadelphia (USP)