The U-Strip – Ultrasonic Transdermal Drug Delivery

U-Strip Sonic Applicator Device

The U-Strip™ (Ultrasonic Strip) is designed to apply a special ultrasonic transmission through the Insulin Patch™, which dilates and enlarges the skin pores, enabling large molecule drugs to penetrate through the sweat pores and then into the bloodstream. The SA Control Unit either attaches to the Insulin Patch™ directly when worn on the arm or through a wire lead to the transducer coupler attached to the patch.

Waist Mounted, On Right Abdomen

U-Strip, waist-mounted

U-Strip Control Screens

The SA Unit allows for Programmable Insulin delivery for both Basal and Bolus Insulin administration. The control unit can be set to deliver insulin doses every hour for a basal program, and to meet mealtime bolus scheduling.

Arm Unit

  • Dimensions: 1.5″ Wide × 3″ Long
  • Powered by a 9-Volt battery
  • Uses a Velcro Strap to fit over Arm

Waist Unit

  • Dimensions: 2.5″ Wide × 5″ Long
  • Powered by a 9-Volt battery
  • Equipped with Belt Clip

Key Features: Equipped With Real Time Easy To Use Touch Screen Controls

Daily Data Summary Phoned Via Monitoring Service To Physician & Patient

  • Delivers Insulin for Both Basal and Bolus needs.
  • Can be set for different Day Time or Night Time delivery profiles.
  • Can be used as a Booster for Type-2 diabetes oral meds. Avoids spikes in glucose during day or night.
  • System detects insulin level in the Patch. / Alarm sounds if patch falls off, battery low, or insulin low.
  • Keeps 60 day memory of glucose readings from patient or sent by RF signal from a glucose monitor.

Closed loop delivery capability

  • Provides Updated Dosing and Glucose Information to patient during the day.

U-Strip Operational Features | PDF pdf icon

The Insulin Patch is:
Totally Non-invasive. No Needles – No skin damage – No catheters.

The U-Strip™ (Ultrasonic Strip) Insulin Patch is designed to apply insulin to the dermis via propagation of a unique and special alternating ultrasonic transmission. The Ultrasound transmission first dilates the pores and then pushes insulin into the dermis region of the skin. From there the insulin enters the blood stream and regulates glucose levels.

Selection Guide U-Strip, waist-mounted
Insulin Patch


Programmable Insulin Delivery

  • Basal Range: 0 to 1.1 U/min. with U-Strip Ultrasonic SA Controller
  • Bolus Range: 1 to 4.0 U/min with U-Strip Ultrasonic SA Controller

Key Patch Features:

  • Dimensions: 4.0″ L × 2.5″ W × 0.20″ Thick
  • Weight when loaded: 9.2 gm Base patch / 21 gm with Transducer Coupler.
  • Unique, Low Profile Insulin Patch has a thin, flexible and light weight design.
  • A Transducer Coupler snaps into the patch and connects to the SA Control Unit.
  • The Patch only delivers insulin when the ultrasound is activated.
  • Patch has proprietary On/Off function.
  • Its unique butterfly shape provides for a full seal under the patch.
  • The Patch is designed for both Arm and Abdominal placement.
U.S. Patents No. 6,908,448 & No. 7,440,798 and others pending internationally.

The U-Wand

The New Science of Cavitation Free, Deep Penetrating Ultrasonic Skincare


The U-Wand™ - This device is the “Only Cavitation Free” Ultrasonic Skincare Delivery System on the market. Its product applicator device has the ability to generate ultrasonic transmissions of variable intensity and frequency on a programmed schedule that dilates the skin’s pores to allow easy acceptance of skincare products. The application goes right under the skin tissue, where the real effect can take place, and not just to the skin surface. The U-Wand™ is a safe, more effective means of enhancing the penetration of skin care active products and serums, even to the most sensitive skin. Ultrasound Sawtooth Waveforms temporarily dilate the pores, and then Ultrasound Square Waveforms gently push the compound into the expanded pores without generating any heat, so there is no damage to the skin or the formulations. This delivery system is ideal for the induction of professional skincare active products such as: Hyaluronic Acid (HA), serums, peptides, vitamins, etc. This light weight, hand held unit is only 5.375 inches long, and is powered by a 9-volt battery.

Disadvantages of Traditional Ultrasonic Devices – The Sine Wave

Sine Wave

This traditional form of Ultrasound can be problematic in regards to applications in skincare:

  • It can create intense heating through cavitation, which can damage or discolor the skin
  • In addition this heating effect can damage a cosmetic compound applied to the skin
  • At low frequency levels, its pore penetration capabilities are very limited


Advantages of the Cavitation Free U-Wand

Alternating Waveforms

Sawtooth and Square Wave – The solution to these product disadvantages is to use an alternating waveform dynamic, which propagates two different waveforms in succession to each other to dilate and penetrate the skin. Just when there could be a generation of heat (cavitation) using a “Sawtooth” waveform, the ultrasonic transmission switches to a Square waveform, creating a momentary drop off of energy, and thereby, ceasing the cavitation formation process, thus producing NO cavitation or spot heating effects. The result is no damage to the skin tissue and no damage to the compound being delivered. In this dual action configuration, the Sawtooth Waves are the dilating force and the Square Waves are the transport force.


U-Wand application

The U-Wand™ applies Ultrasound to the skin, and deposits skincare compounds directly into the pores. The result – More effective skincare treatment for anti-aging skin rejuvenation, anti-wrinkling, acne, skin lightning, and cellulite treatments.


Product Components


The U-Wand and Sonic Cap

1 – The U-Wand™ Ultrasonic Applicator

2 – The Sonic Cap is designed to be used as a protective, hygienic cover for the transducer head of the U-Wand™ and to help spread the gel around the skin. The user applies the product to the desired part of the skin and then runs the U-Wand™ over the area to dilate the pores and allow entry of the formula into the pores of the skin. The cap is disposed of after every use.

Hyaluronic Acid Gel Product

The Anti-Aging Gel is formulated with breakthrough Hyaluronic Acid in a deep Hydration Complex for greater absorption into the skin. Hyaluronic Acid (HA), which occurs naturally in the connective tissues in the body, is the key ingredient in the Advanced Skin Renewal System. With its ability to hold 1000 times its weight in water, Hyaluronic acid is the most powerful natural moisturizing ingredient known to science.

As skin ages, Hyaluronic acid production diminishes, resulting in a loss of elasticity and the formation of wrinkles. Currently the most effective procedures to restore elasticity to the skin are injectable HA Dermal fillers. However, they require in office treatments and are expensive. The Advanced Skin Renewal System is the first non-invasive, needle-free HA treatment that penetrates the skin to restore elasticity at its source.

The Promise


The New Science of Cavitation Free, Deep Penetrating Ultrasonic Skincare

The U-Wand is the Only Ultrasonic, Cavitation Free Device on the market. Working from the inside out, it uses a patented combination of unique ultrasonic waveforms to deliver our Advanced Skin Renewal Hyaluronic Formula deep into the skin going to the very source of aging… Dramatically softening and lessening the appearance of wrinkles, while increasing hydration and regenerating the skin’s fundamental structure. All with NO spot heating negative side effects.

Key Skin Care Categories Targeted by the U-Wand | PDF pdf icon